Indian frankincense extract helps protect the elastin and hyaluronic acid in the dermal matrix and reduces redness and irritation. Boswellia Serrata is an inhibitor of elastase (protease) and hyaluronidase, a life preserver for the dermal matrix. It is also an inhibitor of 5-lipoxygenase, which is why this extract has been used since Biblical times to alleviate arthritis. The enzyme 5-lipoxygenase catalyses the first two steps in the oxygenation of arachidonic acid, which is converted to leukotrienes. Leukotrienes affect inflammation, part of the immune response that defends us from pathogens, but are also mediators of hypersensitivity reactions and allergy.