When you think of an anti-aging system, you really do think about something that encompasses all of the exposed skin on the body. You think about the under-eye area, which normally develops dark circles as we age, you think about facial wrinkles, which obviously need to be addressed with some sort of anti-wrinkle cream, but many people forget about two key areas of the body - the decollete and the back of the hands. All of this exposed skin, neck, upper chest, and hands, have thinner and more delicate skin, which if neglected will show your true age. This is what I consider your "complexion".
Always apply to toner damp skin after the cleansing process and before masking for a firming boost. * Specialized peptides include Chrysin, and Leuphasyl for lightening, brightening, and firming the skin * Coffee Caffeine, Oregano, Green Tea stimulate micro-circulation to reduce puffiness and dark circles * Vital Anti-oxidant Enzymes inhibit free radical formation and detoxify the skin * A Synergistic Blend of Protective Phyto-chemicals protect collagen, reduce inflammation and discourage the visible signs of aging * Regenerative Epidermal Growth Factors repair thinning, aging skin while boosting collagen and elastin production * State-of-the-Art Ingredients include Stem Cells, Keratin, Matrixyl 3000, Anti-Glycation or AGEs Inhibitors * Perricone Cosmeceuticals include Alpha Lipoic Acid, DMAE, Polyphenols, Phospholipids, Pycnogenol, Tocotrienols, Vitamin C Ester, CoEnzyme Q-10 * 13 Essential Vitamins include A B-Complex (B1 B2 B3-Niacin B5-Panthenol B6 B12 Biotin Folic Acid) C D E K feed skin which the body cannot produce * Active Peptide technology yields collagen stimulation, epidermal contouring, and protection from environmental damage * An Energizing and Proprietary Nitrogen Compound utilizes free radicals constructively for cellular energy production * Patented Glycosaminoglycans reduce moisture loss, stop the breakdown of collagen, strengthen and firm the skin * Barrier-Repairing Lipids that are naturally compatible with the skin control moisture loss while repairing and restoring damaged skin
In addition to its internal benefits, CoQ10 can also play a role in making skin look younger. CoQ10 levels decrease as you get older. Indeed, most women over thirty have below optimum levels of CoQ10 in the skin. The lack of CoQ10 results in an impeded ability to produce collagen and elastin. Collagen is important because it makes your skin firm, while elastin gives your skin flexibility. The loss of collagen and elastin causes your skin to wrinkle and sag.
CoQ10 also helps the skin by acting as a strong antioxidant. It helps to neutralize the harmful free radicals that are one of the major causes of aging. Thus, the age-related decline in CoQ10 also your skin is more prone to damage by free radicals.
Using topical anti-aging creams that contain CoQ10 can effectively help fight the signs of aging. The CoQ10 in the treatment can penetrate deeply to provide antioxidants and help create collagen and elastin.
Taking CoQ10 supplements can also help boost skin repair and reduce free radical damage. Like topical treatments, supplements can increase CoQ10 levels in the skin that help maintain collagen and elastin production and protect of your skin from aging. Research has even shown that CoQ10 helps reduce crow’s feet around the eyes.
As we age, our bodies no longer produce the same amounts of certain messaging chemicals that are responsible for regenerating our bodies at regular intervals. To speed up both anti-aging and the 'healing process' we included L-Alpha-Bisabolol, which we sourced purely from Chamomile. In this left-handed form, it far exceeds the ability of Azulene as an anti-inflammatory, burn and wound-healer, and antipyretic.
A significant reduction in wrinkle size in just 28 days. An exclusive blend of six powerful, highly concentrated, 100% active wrinkle relaxing and anti-aging peptides are combined with vitamins and skin moisturizers to create this wrinkle fighting solution with the highest degree of effective ingredients found in clinical studies. SS Serum helps boost natural collagen production and leaves skin looking soft, smooth and years younger.
This blend of state of the art multi-peptides and the super anti-oxidants is most ideal for those displaying moderate to severe signs of aging skin. Incluced are: Aloe barbadensis Juice, Aphanizomenon flos-aqua, Methylsulfonylmethane, Kojic Acid, Lactose, Glycyrrhiza Glabra Extract, Arcctostaphylos Uva-ursi Extract, Morus Bombycis Root Extract, Marine Collagen, Sea Minerals, Rhodophyceae, Nereocystis, Macrocystis pyrifera, Arthrospira platensis, Phaeophyceae Algae, Rhodophyceae Algae, Laminaria Algae Extract, Serum Base, Laminaria Digitata, Fucus Vesiculosus, Phylum Chlorophyta, Phylum Chlorophyta, Sea Fennel, Fucus Vesiculosos, Sea Lettuce, Nori, Himanthalia, Tretinoin, Hydroquinone, Arginine-Cystine-Histidine-Isoleucine-Leucine-Lysine Amino Acids, Spirulina maxima, Konjac Glucomannan, Tocopherol, Argania spinosa Oil, Salix nigra Extract, Rosmarinus officinalis Oleoresin, Azadirachta indica Oil, Glucose, Lactoperoxidase, Glucose Oxidase.
Stimulating Collagen Production
According to Dr. Leslie Baumann's Cosmetic Dermatology, collagen production decreases by approximately 1 percent with each year of age after maturity (about age 21), leading to a loss in firmness and elasticity of skin. So what's an age-conscious woman to do? Here are some options to stimulating collagen production.
1. Lasers Two recently developed lasers are the Genesis and Medlite lasers, which have been reported in the Annals of Plastic Surgery to stimulate skin to make new collagen. Genesis and Medlite lasers are only administered by licensed dermatologists. Most women require three to six treatments, and the results should last three to five years. According to the March 2008 issue of Health magazine, Genesis and Medlite laser treatments are about $400 each. Check with a dermatologist near you for pricing and availability.
2. Facial Light Therapy According to a recent study featured in the March 2008 issue of Allure magazine, LED phototherapy repairs sun damage and increases collagen and elastin production, although lasers and peels have faster, more substantial results, but more side effects, according to Seung Yoon Lee, a dermatologist at the National Medical Center in South Korea. With regards to LED therapy's fewer side effects.
According to Allure magazine, in the study, the researchers treated one side of 61 subjects' faces with a light-emitting diode machine, while 15 others received a one-sided placebo treatment. Twelve weeks later, only the LED-targeted skin had a decrease in wrinkles (26-36 percent) and an increase in elasticity (14-19 percent). LED therapy seems to increase collagen and elastin production, although less significantly than lasers and peels.
3. Retinoid TreatmentsAccording to research by Fisher et. al cited by Dr. Baumann in Cosmetic Dermatology, retinoids are effective in preventing and treating the collagen loss caused by photodamage. UV exposure decreases collagen type I and collagen type III with 24 hours, but treatment of the skin with all-trans retinoic acid prevents the loss of these types of collagen synthesis. In addition, Fisher et. al demonstrated that application of tretinoin inhibits the induction of matrix metalloproteinase genes, which are in part responsible for collagen degradation. Your best option is to talk to your dermatologist about prescription retinoid treatments.
4. Glycolic Acid Peels According to a 1998 study in Dermatological Surgery, glycolic acid treatments increase fibroblasts' production of collagen in vivo (in hairless mice) and in vitro (in human skin fibroblast culture) better than either lactic acid or malic acid. However, if you're deciding between prescription-strength retinoids and over-the-counter glycolic acid peels, you may want to choose the prescription retinoid cream. According to a randomized, placebo-controlled double-blind study, it was found that 0.05% all-trans-retinoic acid was more effective than 10% glycolic acid (a concentration found in at-home treatments) in treating signs of aging.
5. Topical Ascorbyl Palmitate Vitamin C Treatments According to a review in the International Journal of Pharmaceutics, vitamin C triggers collagen production and thereby increasing skin firmness. Dr. Jeannette Graf also adds in Dr. Burgess's Cosmetic Dermatology text, Topical vitamin C increases levels of tissue inhibitors of collagen-degrading matrix metalloproteinases (MMP-1). Vitamin C is particularly potent in conjunction with vitamin E; unfortunately, a 2008 Dermatology Therapy study cited in Best Life magazine found that very few products containing these vitamins remain effective. This is most likely because vitamin C becomes esterified and inactive upon exposure to light, air, and heat. Your best bet? Keep your vitamin C and E product tightly sealed and in a cool, dark place, or consider a stabilized form of vitamin C, although less research has been done on the effects of, say, 2% ascorbyl palmitate than 15% L-ascorbic acid.
6. Topical Peptide Treatments Palmitoyl pentapeptide-3 has been shown to stimulate feedback regulation of new collagen synthesis and to result in an increased production of extracellular matrix proteins (collagen types I and II and fibronectin). For these reasons, palmitoyl pentapeptide-3 is increasingly popular in skin care products.
Palmitoyl oligopeptide is a second sequence of collagen-stimulating peptides. A 2007 study in Dermatologic Therapy suggests that palmitoyl oligopeptide significantly stimulates human skin collagen production in fibroblasts, which may slow the degradation of collagen over time.
7. Treatments with Collagen in the Ingredients Collagen in skin care products acts as only a superior moisturizing ingredient. Topically applying collagen has never been shown to stimulate collagen synthesis or growth. This is because, according to Dr. Leslie Baumann in Cosmetic Dermatology, topically applied collagen is too large to fit through the stratum corneum (uppermost layer of the skin), as collagens have a molecular weight of 15000 to 50000 daltons, whereas only molecules of molecular weight 5000 or less can typically penetrate the skin.
8. Prevent Future Collagen Loss! Don't smoke. Wear sunscreen everyday and limit UV exposure. Eat - and topically apply - lots of anti-oxidants, which has been shown to be more effective than either method alone. Use retinoids or alpha hydroxy acids to increase cell turnover. And exercise - although the link between exercise and skin's collagen production is only implied, always remember, what's good for your health is good for your skin.
If you're like most people, you probably understand that collagen loss leads to aging skin and for that reason you need to use our skin care serum that contains collagen stimulating actives in order to combat its loss. It's important to understand that rubbing collagen into your skin is not going to prevent its loss. In order to combat the loss of collagen, you need to learn how to naturally produce collagen by using products that contain certain active ingredients. It might sound like a difficult task to naturally produce collagen protein. However, it is actually quite simple. A select few ingredients are known to stop the loss of collagen and elastin and stimulate their re-growth naturally. Here are the active ingredients that your skin needs in order to combat collagen loss.
1. Keratin Hands down the best ingredient available for stimulating the collagen production in your skin. Keratin is a protein found throughout the body, which has an important structural role in the skin. The ability to convert natural keratin into a functional form that is readily-available to the skin is a recent breakthrough. This is a new exciting, cutting edge substance. Bioactive Keratin actually stimulates your own collagen to grow again. In fact, it is proven in clinical trials to stimulate not only the regrowth of collagen but also elastin, thereby promoting firmness and elasticity. In short, fewer wrinkles, and more youthful, healthier looking skin. It may help improve your skin's ability to retain its needed natural moisture.
Indeed, studies show a sustained 14% improvement in skin moisture retention over 18 days. Studies also show a sustained improvement in skin elasticity of 42% over 18 days. Bioactive Keratin penetrates your skin deeply and creates an invisible barrier that protects your skin and locks moisture in, which scientific studies show stimulates the production of new skin cells. Keratin stops the loss of collagen and stimulates its production. It also stimulates the production of elastin, another vital protein in the skin.
2. Active Manuka Honey A special honey from New Zealand has unique healing properties. It has been used in skin care for centuries by the Maori people of New Zealand and it's easy to understand why. When used topically, Active Manuka Honey can restore and rejuvenate your skin. It supports the skin cell renewal process and assists in the formation of stronger collagen protein. As an added benefit, active manuka honey is rich in antioxidants and helps to reduce blemishes.
3. Avocado Oil If you want to know how to naturally produce collagen, you need to use face masks or creams that contain avocado oil. Avocado oil is deeply hydrating and highly compatible with the natural oils in your skin. Avocado oil is high in plant steroids, which help to reduce blemishes and age spots. It also helps to regenerate and rejuvenate skin damaged by free radicals. Avocado oil is important because it is scientifically proven to stimulate collagen production and it increases the proportion of soluble collagen in the dermis of your skin.
4. Wakame Sea Kelp Wakame sea kelp extract is an exotic kelp native to the Japanese Sea, which raises the levels of hyaluronic acid in your skin by stopping the enzyme that is breaking it down. This increase will act to greatly smooth out many of the lines on your face. It works by blocking a harmful enzyme in your body called hyaluronidase. Hyaluronidase breaks down hyaluronic acid in your skin. You may think "well who cares." Well, you should because without hyaluronic acid, the elastin and collagen fibers lose their "glue," which leads to a loss of youthful appearance and dark eye circles. If you research this on Wikipedia, you will read, for example, "Hyaluronan is also a major component of skin, where it is involved in tissue repair."
5. CoEnzyme Q-10, Idebenone, Ubiquinone In the 1970s and 1980s, researchers had been studying the potential of Coenzyme Q10 (CoQ10) to reduce free radical damage. A vitamin-like natural compound found in all aerobic organisms, it plays an important role in cellular energy production and is also an effective antioxidant. Trying to boost CoQ10's therapeutic effects, scientists synthesized and tested a variety of its chemical analogs and derivatives. Most of these derivatives were found ineffective or unsafe. However, one of the few exceptions was idebenone. It is closely related to CoQ10 in its structure. However, Idebenone is more effective than CoQ10 in protecting cells from the free radical damage resulting from reduced blood flow. The benefits of this ingredient include shielding skin from environmental damage, improving the appearance of fine lines and wrinkles, and reducing dryness and smoothing skin texture. If you look at the ingredient list for some of the better skin care products, you'll often see CoQ10 listed. CoQ10 is short for Coenzyme Q10, so you may also see it listed this way. CoQ10 is a vitamin like substance that is found in all of our body's cells and is very important for healthy skin. CoQ10 is a powerful anti-oxidant. A lot of skin damage and aging comes from free radicals wreaking havoc in our body's cells. CoQ10's anti-oxidant ability can counter these free radicals before damage occurs. Unfortunately, like many other vital substances, as we age, the amount of CoQ10 in our bodies becomes depleted. CoQ10 can penetrate deeply, it is extremely effective at gobbling up free radicals in your skin. The result is a powerful anti-wrinkle effect, and can also promote collagen and elastin production as well. Together, these main active ingredients are some of the most powerful anti-aging skin care compounds available, and can significantly improve the look and feel of your skin. As you can see, it is possible to stop the loss of collagen protein in your skin, you can stimulate its re-growth. The result will be more youthful skin with improved elasticity, firmness, and tone. You will also notice a dramatic reduction in wrinkles and fine lines. Within days of using this serum, you will see a dramatic difference in the way your skin looks and feels by learning how to naturally produce collagen. So toss those "collagen" creams out and start using our CP Serum for a skin care product that will actually help you re-grow the collagen you have lost!
Idebenone is a Superceutical for The Next Level of Skin Rejuvenation and Free Radical Protection
What is it? Idebenone is the bioengineered cousin of the vital human antioxidant enzyme - CoEnzyme Q10 - but its 60% smaller (so it penetrates the skin) and up to 1000x more effective, simply put its "Super CoQ10".
How does it work? It targets aging at the cellular source - the mitochondria where it helps to revitalize the skin's cells by eliminating excess free radical formation that results from the way cells make energy - in effect it corrects the essence of cellular aging.
How is it unique? Unlike vitamin and botanical antioxidants, Idebenone is a respiratory chain antioxidant, a totally new kind of antioxidant, which can correct the signs of aging and also offers the highest protection against harmful environmental free radical stress with an Environmental Protection Factor of EPF 95, the highest rating of all antioxidants tested.
Why should I use it? Idebenone delivers a whole new level of skin rejuvenation that you cannot get from AHA, Vitamin A, Vitamin C or other cosmeceuticals because of its absolutely unique mode of action. If you have reached a plateau with your current skin care regimen and want the highest level of skin rejuvenation you can only get this from Idebenone the Superceutical.
Idebenone delivers multiple anti-aging benefits: * Helps prevent skin aging at its cellular source * Decreases the appearance of fine lines and wrinkles * Improves uneven skin tone and texture * Brightens the look of skin * Reduces the appearance of unwanted pigmentation * Offers maximum protection against environmental stress * EPF 95
6. Alpha Lipoic Acid Lipoic acid is the strongest and longest lasting antioxidant. Lipoic Acid is both water-soluble and oil-soluble. Extremely powerful antioxidant that helps Vitamins C and E work more effectively in the skin. 400 times more powerful than Vitamin C as an antioxidant. Increases gluathione, the body's most important antioxidant. Powerful anti-inflammatory. It has anti-inflammatory qualities, which can be helpful in reducing the redness associated with rosacea, acne and sensitive skin types. It reduces the appearance of wrinkles, fine lines, dull skin, puffy eyes, and dark circles. This means it can fight free radicals in any part of a cell (intracellular) as well as the spaces in between the cells (intercellular). Lipoic acid increases the cell's metabolism, which allows the cell to take in more nutrients, eliminate more wastes, and replace more damaged components. It increases the free radical fighting properties of other antioxidants. Lipoic acid activates the transcription factor AP-1 that produces collagen-digesting enzymes that digest damaged collagen. Damaged collagen is responsible for wrinkles and scars so eliminating the damaged collagen can reverse aging. Lipoic acid is credited with reducing under-eye puffiness, sallow skin, enlarged pores, redness, lines, wrinkles, and acne scars.
Calcium Calcium is a regulator of every organ in the body and the skin is no exception. The skin guards its calcium level very carefully and the calcium integrity of the upper epidermis regulates at least four major skin functions and possibly others that have yet to be determined.
Even though we are constantly shedding skin cells, the skin maintains a constant thickness of living layers. It therefore must have a means of determining its present thickness and a means of stimulating cellular division to replace these cells. At times cellular loss can be fast and at other times it may be slow. The skin must respond correctly. The calcium content of the upper epidermis is the measuring tool and the regulator of cell differentiation. Differentiation is the point at which an immature cell in the basal epidermis becomes an end cell, or a terminal cell and begins moving upward through the epidermis, toward eventual death and exfoliation. Until a basal cell differentiates, it is in a state of suspended animation
In the upper epidermis, when cells die and pass through the stratum granular layer they are stripped of their calcium content. If the skin experiences injury or excessive exfoliation, volumes of cells die and pass into the stratum corneum. They are stripped of their calcium and the calcium content of the upper epidermis becomes very high. Keratinocytes (skin cells) then absorb more calcium, which triggers the production of an enzyme named protein kinase C (PKC).
PKC travels out of the keratinocyte cells and goes from the upper epidermis down into the basal epidermis. It passes into immature (undifferentiated) keratinocyte cells and stimulates chromosomes 1 and 10 (chromosomes that regulate keratin production). The cells then differentiate (begin producing keratin) and move upward to replace the lost cells and eventual exfoliation. These newly differentiated cells are replaced by new basal cell division.
In this manner, the skin's calcium content regulates cell differentiation (and cell division) and controls the thickness of the epidermis. High concentrations of upper epidermal calcium thereby cause rapid cell turnover and low concentrations of upper epidermal calcium cause slow cell turnover. Cell turnover can be up-regulated by increasing upper epidermal calcium and SuperSkin Ultra Elixir produces this result. When calcium application is used in conjunction with peeling or microdermabrasion, resurfacing of the skin is faster and more profound. Conversely, resurfacing procedures on patients with low skin calcium content is slow and ineffectual.
As a second skin function, calcium regulates normal skin color by stimulating melanocytes (pigment producing cells) at the same time it causes differentiation of immature cells. Thirdly, calcium regulates lipid barrier processes. Peeling, microdermabrasion and cold winter weather strip the skin's moisture barrier. High calcium content in the upper epidermis helps maintain continual and efficient barrier functions. Patients with dry skin, or dry skin due to weather, respond well to topical calcium treatment. In the case of microdermabrasion, Bio-Essence Nighttime Calcium Complex can significantly reduce the dryness that is typical with this procedure and increase cell turnover simultaneously.
The National Cancer Research Institute (NCRI) has done exhaustive study of the functions of calcium within the skin. They observed that people with low skin calcium content experience greater premature aging of the skin and greater incidence of skin cancer. People with high skin calcium content experience less premature skin aging and less incidence of skin cancer. These observations were the reasons for their interest in calcium and their research produced much of the above information.
The fourth function of calcium within the skin is to stimulate the production of the skin's own age-protective and cancer-protective antioxidants. This proved to be the relationship between calcium and cancer that the NCRI was seeking. While science does not know the precise mechanism or process, calcium content has been directly linked with the production of catalase and indirectly linked to superoxide dismutase (two of the skin's most powerful antioxidants). Antioxidants prevent damage to the skin's components such as collagen. Antioxidants prevent DNA damage that lead to premature aging of the skin and skin cancer. Topical calcium products therefore provide anti-aging benefits and enhance skin cancer protection.
Calcium is an extremely powerful tool for skin rejuvenation and, in the not too distant future, it will receive media attention and marketing focus. Like zinc, ABSilk is one of a very small number of skin care manufacturers that understands calcium and formulates products to include it. The formulating process is complex since calcium must be combined in exact ratios with other biochemicals for cellular absorption to occur.
Pepha-Tight is a highly purified biotechnologically produced extract from the microalgae Nannochloropsis oculata combined with a well balanced fraction of polysaccharides. Pepha-Tight functions as a skin tightener which provides immediate tightening to the skin. It has been shown to protect human fibroblasts from oxidative stress, simultaneously increasing the formation of collagen-l thereby promoting a long term tightening effect through the strengthening of the skin's connective tissue. Pepha-Tight can be used for all skin tightening applications including lifting products, masks, decollete treatments, gels and serums.
Collagen and Collagen Synthesis Many ingredients claim to help you naturally produce more collagen, but D (SS) Serum actually contains REAL ingredients that naturally stimulate the collagen production in your skin. It is very hard to find a product that contains all these collagen boosters because it is complex to properly manufacture, takes much longer to and is expensive to produce. The most powerful substance to help keep skin stay young, soft and vibrant is collagen. Collagen is what gives young skin its firmness. It is a natural protein that provides our skin with structural support. By replenishing the collagen levels in our skin, the aging process is drastically slowed down and existing wrinkles are quickly reversed or repaired. Collagen helps skin become thicker, more youthful and elastic with hydrated skin so you begin looking younger within the first week. Fine lines and wrinkles begin to disappear and deeper wrinkles recede within three weeks, the face actually undergoes a visible change of youthful contour. Collagen is the glue that holds the body together. Collagen is the most abundant structural protein in the body 60% of the body is made up of connective tissue and collagen represents 80% of all connective tissue. 75% of the dermis consists of collagen and it accounts for 90% of dermal volume. From the age of approximately 25-35 years onwards the body loses collagen at a rate of 1.5% per annum. Collagen is not available from food. There are many face-lift programs and treatments on the market. But, these mostly work on the surface of the skin.
Beta Glucan - Recent studies with several hundred women, given a cosmetic regimen of which a topical cream containing beta glucan was a major part. The effects on the signs of aging in the skin were evaluated. Compared with the control group, A 27 percent improvement in skin hydration was observed after eight weeks of using the regimen twice a day. An improvement in lines and wrinkles of 47 percent was measured, firmness and elasticity increased by 60 percent, and skin color improved by 26 percent. The rate of skin renewal increased by 34 percent. These dramatic results were achieved because beta glucan rejuvenates the skin's cells by invigorating the macrophages. You can learn more about macrophages by searching in our library. "Specialized" versions of macrophages are found in almost every area of the body, and the skin is no exception, where they are known as "Langerhans" cells, after the scientist who discovered them. These Langerhans cells are found in all parts of the skin, but more so in the upper layers called the epidermis. They're referred to also as dendritic macrophages because dendrites the spiderweb-like tentacles that emanate out of them literally permeate throughout the skin, almost like an intricate spiderweb or latticework, and these serve as a source for where the macrophage's receptors can be stimulated. So when you apply a beta lotion or cream topically, it gets exposed to the dendrites of these Langerhans cells, and stimulates or activates them. It's relatively easy from there to understand how supporting immune cells in the skin can lead to healthier skin, and enhanced wound healing, but it's less obvious how topical application of beta glucan can reduce the appearance of aging. So let's take a quick look at what happens when we age, and wrinkles and grainy-looking skin appears. First of all, the reason animal cells "stick together" is because of a substance called collagen. It's the "glue" that binds the cells. What happens when we age (and aging can be defined as the sum total of all the insults we receive, from sunlight, chemicals, poor diet, etc.) is that our skin cells die. If our immune system is healthy, these dead cells are unglued from the collagen by an enzyme released from the macrophage, called collagenase. Then the phagocytes come in and gobble up the debris. This gives room for the new cells to grow in its place. The next step in this process is that epidermal (or "epithelial") growth factors are secreted. These are proteins that act like e-mails or fax messages that are sent out by the macrophages to another type of cell called fibroblasts. The fibroblast comes back to this area where the new cell growth was created and starts to produce collagen again. Without this process, there would be crosslinking of collagen, which creates wrinkles. There would also be granulization on and around dead or damaged tissue, all of which adds up to what we think of as an appearance of aging. The problem, in our modern world, is that so many things tend to destroy, damage or weaken the Langerhans cells. Ultraviolet light from excessive exposure to sunlight, chemicals in soaps and cosmetics, chlorine in the water in which we bathe these all have a negative effect on the immune cells contained in our skin and contribute to what we now consider the "normal" appearance of aging. That is why it's extremely difficult to maintain a healthy skin today without giving it a little help. When the immune system, as found in the skin, is functioning properly, the dead and damaged tissue is removed, there is rapid healing, and the result is a smooth repaired area, with good tensile strength. The key to all this, again, is the healthy functioning of the macrophage. And the key to supporting the macrophage is beta glucan. The process by which beta glucan supports overall dermatological health has also been shown to aid wound healing. Several studies have shown dramatic improvements in healing rates (see reference list) with topical application of a salve containing beta glucan. So, once you find a high-quality beta glucan cream or salve, make sure you keep it as a permanent part of your household supplies. For best results, also add it to your sunscreen when venturing outdoors.
The Fountain of Youth is pure and concentrated as we use it, a glycosaminoglycan present in the intercellular matrix of skin where it has a conservative, structure balancing and shock-absorbing role. It is currently popular as the ingredient found in the cosmetic injection, Restylane. It naturally occurs in the body, but diminishes as we age or as our bodies become less hydrated. Hyaluronic Acid is the glue that binds collagen and elastin in place. It contains amino-polysaccharides called glycosaminoglycans (GAG's), which help increase elasticity and mobility between cells and help the skin repair, renew, and revitalize itself. Hyaluronic Acid is normally found in the joints, the deeper layers of skin, in foetal skin and in the umbilical cord. Medical graded Hyaluronic Acid is usually helpful to diminish the incidence of post-operative adhesions, as a viscoelastic agent in intra-ocular surgery, also as a synovial replacement fluid; and is used to facilitate the healing and regeneration of surgical wounds. The unique properties of Hyaluronic Acid make it the ideal moisturizer. Hyaluronic Acid plays a crucial part in tissue hydration, lubrication and cellular behavior, and has the ability to hold more water than any other biological substance. Its incomparable hydrating properties produce augmented smoothness, softening and decreased wrinkles. Hyaluronic Acid has also proven to give excellent results in the reduction of dryness, itching and burning of the skin. It offers a perfect environment for the reproduction of new cells and healing following skin peels. Hyaluronic Acid is a major component of the extra-cellular matrix that circumscribes quickly dividing cells. It has been demonstrated to be an integral factor in the rapid and scarless wound healing seen in fetal and neonatal tissues. Moreover, the cellular actions precipitated by Hyaluronic Acid are integral to the apparently magical chemical processes of fetal development. It is well documented that fetal tissues have large amounts of Hyaluronic Acid and that decreasing Hyaluronic Acid quantities correlates with aging and wrinkling. Therefore any practical attempts to extend and recapture youth by revivifying damaged tissue should consider the inclusion of this molecule.
Essential Oils - Nature's Answer To Oxygen Deficiency If there is any one BIG reason for you to use essential oils everyday, it can be summed up in one word...OXYGEN! Essential oils are loaded with it, at least 50 times more oxygen than what the plants give off from which they are derived. While essential oils may contain hundreds of different elements, three primary elements common to all oils are hydrogen, carbon and stabilized OXYGEN. So each time you inhale essential oils or apply them to your body, you are enriching your body with needed oxygen to purge toxins and fight off disease causing pathogens. This is why the use of essential oils on a daily basis can help you develop a superior immune system, and why people who use the oils (several times daily) seldom experience illness and disease. One of the incredible aspects of essential oils is their ability to penetrate and carry nutrients through the cell wall to the cell nucleous. Dr. Radwan Farag, Ph.D., head of the bio- chemistry department at Cairo University, is the man accredited for documenting the oxygenating and antioxidant activity essential oils afford. When the viscosity of blood is reduced, it's velocity increases. By increasing its velocity, our blood is able to deliver greater amounts of oxygen to tissues. When essential oils are introduced to the blood stream, they increase circulation, thereby increasing oxygenation. As the blood delivers nutrients and oxygen to the cells for feeding, it is the oxygenating molecules that penetrate and carry nutrients through the cell wall to the cell nucleous for feeding and oxidation. As the body grows oxygen deficient, individual cells begin to suffer. Without adequate oxygen, cells become nutritionally starved and become a garbage pit for waste and toxins, Deprived of nutrition, the cell protects itself by thickening its outer wall...making nutrient delivery even more difficult. This in turn causes cell deterioration, which can lead to cell mutation. It is in this state that the body becomes a host for disease causing pathogens. Due to their high oxygen content, essential oils are natures most effective catalyst and delivery agent for feeding cells. Rich in oxygen, they pass through the thickest cell walls with the greatest of ease (to maintain or begin a restorative process). This is just one of many ways in which essential oils help us. Because of their vast complexity and human individuality, modern science is just now beginning to realize we have only scratched the surface in understanding how essential oils work and interact within the human body.
White Tea was preceded by green tea, known for being 200 times more potent than Vitamin E in its ability to destroy free radicals that can cause imperfections and premature aging of the skin. But research points to WHITE TEA -- as being three times more effective an antioxidant than green tea. Independent scientists at Case Western Reserve University in Cleveland have recently found that when a white-tea serum was applied to the skin before sun exposure, the polyphenols in the tea helped protect vital cells from damage during UV over-exposure. Without these, the skin is more prone to premature aging.
EFA-3 contains a unique ratio of Essential Fatty Acid extracts from Ultra-Pure Olive-derived Squalane from Italy along with Emu Oil to match that of the human skin.. Delivering all three Essential Fatty Acids, Omega-3, Omega-6, and Omega-9, directly into thirsty skin for immediate lipid replenishment. Because the body is not able to create Essential Fatty Acids on its own, topical supplementation is vital for soft, vibrant, younger-looking skin.
Anti-microbial Peptides repair disruption of the skin by acne inflammation, infection, sun damage, disease, lesions due to trauma, surgery, burns, accidents, or by chemical, dermabrasion or laser procedures used for skin renewal. AMP generates a signal to the natural immune system and initiates responses that may or may not be effective in a) preventing an impending invasion from surrounding microbes, b) inducing the production of antimicrobial peptides on the surface of the skin, and c) triggering the regeneration of new healthy cells to replace those damaged. Anti-microbial peptides (AMPs) protect the epithelial surfaces of all multicellular organisms from environmental microbes. Collectively AMPs exhibit activity against bacteria, fungi, viruses, and protozoa. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid-rich membranes. Once in a target microbial membrane, the peptide kills target cells through diverse mechanisms. In man the best studied antimicrobial peptides expressed on skin and its appendages are the defensins, the cathelicidin LL37, and the recently described AMP, psoriasin. Most of the known AMPs are inducible. Topical agents such as the glycoconjugates stimulate local expression of epidermal AMPs and represent a novel class of skin care product. Decreased levels of these peptides have been noted for patients with atopic dermatitis and Kostmann's syndrome, a congenital neutropenia. In addition to important antimicrobial properties, growing evidence indicates that AMPs alter the host immune response through receptor-dependent interactions. AMPs have been shown to be important in such diverse functions as angiogenesis, wound healing, and chemotaxis. As our knowledge of AMP biology expands, the precise role and relevance of these peptides will be better elucidated.
Copper Peptides Glycosaminoglycans (GAGs) tightly binds divalent copper cations (Cu 2+) and form copper peptides, with reportedly have skin regeneration properties. The concentration of copper is notable, but copper peptides have been shown to be active in nanomolar amounts. Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing. Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery. The greatest interest in copper peptides is in the area of reversing the effects of human aging and ultraviolet damage on human skin. During aging, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number. A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
Marine Soluble Collagen is collagen that has been processed to enable transdermal delivery. Marine collagen derived from salmon and marine source, naturally contains DMAE. DMAE, made popular by Dr. Nicolas Perricone, is a naturally occurring substance that facilitates the synthesis of a neurotransmitter acetylcholine, which help to maintain skins firmness and facial tone. DMAE also stimulates the synthesis of phosphatidylcholine, an important component of cell membranes. Its soluble state, being fractionated for transdermal delivery, naturally encapsulates for skin absorption penetrates in the pores of the skin. This provides a significant soluble native collagen inflow, which has the following effects on the skin: It reduces wrinkles, is ultra hydrating, increases tone of the skin, helps healing, supports the growth of cells of the skin, procurez a bright and radiant complexion and it gives an ultra smooth and soft skin.
Vitamin K with Haloxyl has amazing anti-aging and anti-inflammatory properties that are wonderful for the eye area and has also been used topically to alleviate the discomfort and irritation following chemical peels and surgery (with the doctor's permission). Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-3 have great firming and toning properties while the Chrysin, and Hydroxysuccinimide help lessen the under-eye circles and inflammation, and the Theophylline Sillinate is a super active caffeine derivative to draw excess fluid and reduce puffiness. This blend has green tea, cucumber, and chamomile to promote the healing of damaged skin and bruises as wekk as decrease the appearance of: redness of rosacea; dark under-eye circles; spider veins of the face; broken and distended blood vessels; and bruises (must be used two weeks prior to surgery and after surgery).
Vitamin E has been shown to have a wide variety of skin benefits. Many studies have shown that vitamin E can help decrease the effects of psoriasis, erythema, and may help in reducing the risk of skin cancer. Vitamin E has also been shown to significantly help in the reduction of scaring from wounds and has been shown to help reduce the appearance of stretch marks on the skin.
Bioflavonoids or Vitamin P may be active in preserving the structures of capillaries, have an antibacterial effect and promote circulation. They have been shown to aid the effectiveness of other vitamins when used in combination.
Aloe Vera has marvelous medicinal properties. Aloe Vera healing comes from Growth Factors, Amino Acids, and minerals such as Zinc, as well as Polysaccharides. These biologically active agents synergize to give us the power of Aloe Vera. Epidermal and Fibroblast growth factors stimulate the Fibroblast directly for growth and repair. The cells as a result migrate within the wound in a proper manner to increase wound healing. Scientists have discovered over 150 nutritional ingredients in Aloe vera. There seems to be no single magic ingredient. They all work together in a synergistic way to create healing and health giving benefits. The ten main areas of chemical constituents of Aloe vera include: Glycoproteins, Gibberellin, Auxin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols. The amino acids in Aloe vera are the building blocks of protein and influence our brain function. Humans require 22 amino acids and the body will make all of them except for eight essential amino acids which our body gets from the food/drinks that we take in. Every one of the essential amino acids are available in Aloe vera and they include isoleucine, leucine, lysine, methionine, phenylalanine, threonine, valine,and tryptophan. Some of the other non-essential amino acids found in Aloe vera include alanine, arginine, asparagine, cysteine, glutamic acid, glycine, histidine, proline, serine, tyrosine, glutamine, and aspartic acid. Located in the sap of the leaves you will find twelve anthraquinones, a phenolic compound that has stimulating effects on the bowels and antibiotic properties. In small amounts the anthraquinones do not have a purgative effect. They help with absorption from the gastro intestinal tract and have anti-microbial and pain killing effects. Too many anthraquinones can produce abdominal pain and diarrhea. The most important anthraquinones are aloin and emodin. They are anti-bacterial, anti-viral, and analgesic. The anthraquinones in Aloe vera breakup residue, pus and lifeless cells, bring blood to the region and flush out material from the wounds and ulcers. Enzymes act as biochemical catalysts that break down the proteins we eat into amino acids. The enzymes turn the food we eat into fuel for every cell in our body, enabling the cells to function and work efficiently. The main enzymes found in Aloe vera include Amylase (breaks down sugars and starches), Bradykinase (stimulates immune system, analgesic, anti-inflammatory), Catalase (prevents accumulation of water in the body), Cellulase (aids digestion - cellulose), Lipase (aids digestion - fats), Oxidase, Alkaline Phosphatase, Proteolytiase (hydrolyses proteins into their constituent elements), Creatine Phosphokinase (aids metabolism), and Carboxypeptidase. The next thing we need to ask ourselves is what fuels the enzymes? The key is the vitamins and minerals we take in. For instance if we lack in zinc and/or Vitamin B6, our body will not be able to break down or use protein. Because of the healing properties of Aloe vera and its synergistic action, the body receives what it needs to work properly. Aloe vera, an anti-oxidant rich plant, contains vitamins such as A, C, and E plus the minerals, zinc, and selenium. Anti-oxidants help boost the immune system and combat free radicals in the body. It also contains Vitamins B1, B2, B3, B5, B6, and B12 along with choline, calcium (teeth and bone formation, muscle contractions and heart health), magnesium(strengthens teeth and bones, maintains healthy muscles and nervous system, activates enzymes), zinc (speeds up wound healing, mental quickness assists with healthy teeth, bones, skin, immune system, and digestive aid), manganese (activates enzymes, builds healthy bones, nerves and tissues), chromium (assists with protein metabolism and balancing of blood sugars), selenium which all influence our brain performance. Additional minerals found in Aloe vera include copper (important for red blood cells, skin and hair pigment), iron (involved in oxygen transportation and making of hemoglobin in red blood cells), potassium (helps with fluid balance), phosphorus (helps build bones and teeth, assists with metabolism and body pH), and sodium (regulates body liquids, helps with nerve and muscle performance, and helps deliver nutrients into body cells). Aloe vera also contains the trace minerals of rhodium and iridium used in cancer and tumor research experiments. Another component of Aloe vera consists of the lignins, a major structural material of cellulose content, that allows for penetrative properties. Aloe vera can soak into the skin up to seven layers deep. Lignins penetrate the toughened areas of the skin being beneficial for skin problems such as eczema and psoriasis. The next elements of Aloe vera we will discuss include monosaccharides and polysaccharides. Monosaccharides contain the simple sugars which include glucose. The polysaccharides are the more complex long-chain sugars involving glucose and mannose or the gluco-mannans. These sugars are ingested whole from the stomach. They do not get broken down like other sugars, and appear in the bloodstream in exactly the same form. This process is known as pinocytosis. Once in the blood stream, they exert their healing and immuno-regulating effect. Some of these polysaccharides are not absorbed but stick to certain cells lining the gut and form a barrier preventing absorption of unwanted material so helping to prevent a leaking gut syndrome. The sugars are also used in moisturizing preparations. One polysaccharide, acemannan, is known for its ability to restore and boost the immune system by stimulating the production of macrophages and improving the activity of T-Lymphocytes by up to 50 %. Acemannan produces immune agents such as interferon and interleukin which help to destroy viruses, bacteria, and tumor cells. Acemannan improves cellular metabolism by normalizing cellular function and regulating the flow of nutrients and wastes in and out of the cells. It knows how to destroy parasites and fungus. In some AIDS patients, it even protected the immune system from the toxic side effects of AZT. Carrington Laboratories in the United States have separated the acemannan from Aloe vera. The product is sold as Carrisyn and is being used for treatment of AIDS and Feline leukemia. Many sources stated that Aloe vera has mucopolysaccharides, nitrogen containing polysaccharides, found in animals and bacteria. A regulation and testing board for Aloe vera products known as the International Aloe Science Council concludes that some people are misinformed and confused on terminology. The Aloe has polysaccharides but not mucopolysaccharides. Aloe vera contains salicylic acid which is an aspirin-like compound with anti -inflammatory, analgesic, and anti-bacterial properties. It has anti-pyretic properties for reducing fevers. Other constituents of Aloe vera would include prostaglandins, tannins, magnesium lactate, resins, mannins, proteins such as lectins, monosulfonic acid and gibberlin. Another constituent of Aloe vera includes saponins. These are soapy substances from the gel that is capable of cleansing and having antiseptic properties. The saponins perform strongly as anti-microbial against bacteria, viruses, fungi, and yeasts. The plant sterols or phyto-steroids in Aloe vera include Cholesterol, Campesterol, Lupeol, and B (Beta sign) Sitosterol. The plant steroids have fatty acids in them that have antiseptic, analgesic, and anti-inflammatory properties.
Fish Collagen Available from only one laboratory in Europe. Identical to human collagen and 100% absorbable through the skin. The best, most effective and most affordable antiaging skin care product. Can be used over your entire face or body without ridiculous costs.
Human Collagen Not absorbable through the skin. Must be administered via injections. Provides very localized results. Is a poor candidate for stretch marks or wrinkle cream. Is an expensive alternative for whole face or body treatments.
Animal Collagen Normally bovine collagen, which is not well-suited for use in wrinkle cream. Causes many side effects and reactions. Not a match for human collagen and has a very low absorption rate. Better used for painful injections
Free Radical Wrinkle Cream
Free radicals destroy collagen in the skin. Free radical wrinkle cream helps prevent the destruction of collagen. This is wonderful if you're 20 and no damage has occurred. Free radical wrinkle cream will not repair or replace collagen that has already been lost.
Human Growth Hormone (HGH)
HGH acts to regenerate the messengers in the body that rejuvenate cells. However, collagen is not a cell, it is a protein within a cell. While HGH may have some benefits as an antiaging skin care solution, it cannot take the place of a fresh collagen supply.
Cosmetic Surgery or Office Procedures
Painful, expensive, sometimes dangerous with lengthy recovery times and limited results. You get longer-lasting results with no pain and a fraction of the expense when you use Collagen 3H antiaging skin care formula.
Serums or Actives are the strongest ingredients and the crux of any skin care line, used to treat skin for the correction of skin conditions. Potent blending specific for targeted skin correction, the formulas are very concentrated which is reflected in the size and cost of the product and must be used sparingly. Serums last about two months depending on use. Serums are compatible with one another and with other brands. Serums may be used in any combination, at anytime, in any order.
Serums are formulated to promote quicker skin cell turnover, reinforce the skin's natural defense barrier, and regulate the skin's metabolism while removing toxins and waste. Feeding skin powerful vitamins and skin nutrients will help restore skin from sun, free radical, environmental damages, and protect the hydro-lipidic film to create a comfortable luminescent complexion. Designed as spot treatment for eyes, expression lines, or blemishes. Also designed as area treatment for larger areas to help control and heal the natural aging process, widespread oily T zone, tissue congestion, loss of elasticity with a sagging appearance, or sun damage with age spots and discoloration. Light frequent applications will more quickly correct a severe condition.
Serums are not moisturizers. Follow with a hydrator to add water hydration for dehydrated skins then a moisturizer to seal in that hydration and add lubrication to dry skins. However, for some oily skins the serum will suffice and may not need a moisturizer.
20% Matrixyl 3000 in Hyaluronic Acid with Marine Collagen blended to create our long-term and short-term anti-wrinkle system.
Proteasyl TP 8657
Pisum Sativum (Pea Peptide) Extract strengthens skin's elasticity, protects and repairs epidermal proteins that promote the production of collagen. 35% increase in skin firmness over 3 month period. Firms and tightens the skin through the implementation of proteins and essential amino acids that promote the production of collagen, antioxidant, anti-wrinkle, promotes membrane lipid synthesis
Acetyl Tetrapetide-2 (amino acid) stimulates natural i mmune defenses and increases the thickness of the epidermis as well as supports the restoration of the dermal papillary pattern. Stimulates detoxification processes to eliminate excess fluid retention and blood stagnation, regulates peripheral bloodflow to reduce the appearance of dark circles and bruising
(Pentapharm) - Palmitoyl Tripeptide-5 & 6 (amino acid) is a powerful combination of these two peptides which has a significant impact on the production of collagen and minimizes fine lines and wrinkles, moisturizes and firms. 32% improvement in skin tonicity over 3 month period .
(Pentapharm) - Palmitoyl Tripeptide-5 (amino acid) is a peptide that actively stimulates collagen production and has the ability to compensate for any damaged collagen in the skin. Increase in collagen synthesis of 119% over 84 days.
Myrtus Communis Leaf Extract is an active ingredient that is specifically involved in cellular longevity with antioxidant and free radical fighting properties along with glycation inhibitors which are implicated in aging. Stimulates micro-circulation to improve absorption and circulation
Long-term anti-wrinkle system: Matrixyl stimulates collagen synthesis and dermal matrix repair, a synthetic pentapeptide that mimics a fragment of Procollagen by stimulating the matrix molecules to reduce the appearance of wrinkles. In formulations, use 3-8% as recommended by the manufacturer.
7% DMAE stimulates cetylcholine release which triggers a response in the muscles of the face. This activity creates a firmer facial tone and less sagging. DMAE is used topically to reduce fine lines and wrinkles, showing a noticeable difference within 20 minutes of application.
7% Idebenone is the new key word in firming skin care. Prevage retails for $100.00 an ounce and is only a 1% strength. My Patricia's Selection Serum costs less and is stronger with a 7% content! Idebenone is a newly discovered, super-powerful anti-oxidant that can effectively fight the signs of aging brought on by factors such as age, sun damage, and smoking. Antioxidants play an important role in promoting collagen production which is crucial for healthy skin and for enabling skin tissue growth and repair of damaged skin tissues. Idebenone improves the appearance of fine lines, helps reduce dryness, and smooths the skin texture. As Idebenone is a free radical scavenger, it protects the cells from environmental damage. Studies show that Idebenone is more powerful in preventing cell damage than the top 5 popular antioxidants.
80% Hyaluronic Acid plays an important role in tissue hydration, lubrication and cellular function. Hyaluronic acid, often described as "nature's moisturizer", is one of the most hydrophilic (water retaining) molecules in nature and is able to hold more water than any other natural substance. Hyaluronic Acid's unmatched hydrating properties result in increased smoothness, softening and decreased wrinkles.
7% Alpha Lipoic Acid is the most powerful, strongest, and longest lasting anti-oxidant that is both water-soluble and oil-soluble. This means it can fight free radicals in any part of a cell (intracellular) as well as the spaces in between the cells (intercellular). Lipoic acid increases the cell's metabolism, which allows the cell to take in more nutrients, eliminate more wastes, and replace more damaged components. Lipoic acid is the strongest and longest lasting antioxidant. It increases the free radical fighting properties of other antioxidants. Lipoic acid activates the transcription factor AP-1 which produces collagen digesting enzymes that digest damaged collagen. Damaged collagen is responsible for wrinkles and scars so eliminating the damaged collagen can reverse aging. Lipoic acid is a well-known natural substance found in certain foods and also produced in the human body. It has an impressive array of potentially beneficial mechanisms of action:
* Lipoic acid is a potent and versatile antioxidant. * It is a co-factor in a key biochemical pathway responsible for energy production in the cells (citric acid cycle). * It inhibits cross-linking which is the formation of chemical bridges between proteins or other large molecules. Cross-linking contributed to the aging process by causing hardening of arteries, wrinkling of the skin, and stiffening of joints. * It has moderate anti-inflammatory effect. * Finally, it has a capacity, albeit a modest one, to neutralize and remove from the body a variety of toxic metals.
You may have heard of alpha lipoic acid as "the miracle in a jar" for its anti-aging effects. It's a newer, ultra-potent anti-oxidant that helps fight future skin damage and helps repair past damage. Alpha lipoic acid has been referred to as a "universal anti-oxidant" because it's soluble in both water and oil, which permits its entrance to all parts of the cell. Due to this quality, it is believed that alpha lipoic acid can provide the greatest protection against damaging free radicals when compared with other anti-oxidants. Alpha lipoic acid diminishes fine lines, gives skin a healthy glow and boosts levels of other anti-oxidants, such as vitamin C. Some researchers claim it is an antioxidant 400 times more potent than Vitamin C or E. Beyond anti-free radical action, it also plays a role in cell energy, contributing to a healthy looking, glowing complexion.
Vitamin C Ester is an agent that is not only water soluble, but also is fat-soluble. This allows for rapid penetration into all layers of the cells of your body for maximum results. This version is also much gentler to the skin and more stable in topical compositions retaining it's efficacy and active ingredients for around 2 years rather than 2 months.
15% Matrixyl, also known as Palmitoyl pentapeptide-3, came into being through the work of two branches of dermatological research: the search for substances that accelerate recovery from skin wounds and investigations into what causes wrinkles. When skin is wounded, tiny cells called fibroblasts change their characteristics (kind of like changing into their work clothes) and help to repair the damaged tissue and assist in the process of forming new tissue. Part of their job is to manufacture new collagen, an important component of connective tissue.
Matrixyl is a lipopeptide that stimulates the matrix molecules in the skin, particularly collagen and fibronectin. Simply, it sends a chemical message to the cells to make new collagen. Collagen is a protein - through the natural processes of aging, collagen in the skin is lost resulting in wrinkles. Matrixyl is a fatty acid mixed with amino acids. The active ingredient in Matrixyl is called Micro-collagen which is a peptide. When applied to the skin, Matrixyl penetrates the deeper layers of the skin.
It is concluded from "Sederma", where our ingredient Matrixyl is produced, that after a wide range of tests carried out to study the cosmetic potential of the newly discovered protein fragment, Pal-KTTKS Micro-collagen, leads to remarkable results. Matrixyl with Micro-collagen contributes to the characteristics of a younger, smoother, less wrinkled skin.
Fibroblasts never completely lose this ability to create more collagen, even in mature skin. After all, even older people's wounds heal eventually. But as you grow older, your collagen levels dwindle, and your taut, dewy skin dries out and crinkles. Wrinkles are nothing more or less than the depletion of collagen in the skin, according to Robert Garonne, Professor of Cell Biology at Lyon University in France."
Coenzyme Q-10 is one of the essential cogs in the biochemical machinery that produces biological energy (ATP) inside the cells. CoQ10 is an anti-oxidant that helps neutralize harmful free radicals, which are one of the causes of aging. It can help boost skin repair and regeneration to reduce damage. Furthermore, CoQ10 is a small molecule that can relatively easily penetrate into skin cells.
Pro-Vitamin B5 (dl-Panthenol) a humectant effective at counteracting the dryness that occurs in aging skin and increases the moisture retention capacity of the skin which allows dry skin to stay supple and elastic longer. It is anti-inflammatory and stimulates skin regeneration. Niacinamide and Panthenol improve the condition of the skin's moisture barrier, a function considered by dermatologists as critical to healthy skin.
Niacinamide (Vitamin B3) is the biologically active form of niacin, Vitamin B3. Niacinamide increases the rate of skin exfoliation and increases moisture barrier repair. Studies have shown it to be useful in increasing synthesis of collagen and lipids, inhibiting the transfer of melanosomes and decreasing inflammation. "Niacinamide is one of the vitamins that I believe we'll hear more and more about in the coming years. Already, topical 4% niacinamide has been shown to be beneficial in the treatment of papular and pustular acne in a 4% gel, as well as the improvement of skin cancer and its anti-tumor characteristics,'' Dr. Draelos. SOURCE: American Academy of Dermatology. Niacinamide is an amazing antioxidant that works for aging and acne related issues making it the perfect addition to the Face Firming Serum.
Chlorella Vulgaris Extract has been shown to protect collagen and elastin fibers against the enzymes responsible for their degradation, namely, collagenase and elastase. As we age, it is the destruction of collagen and elastin by our own body, accelerated by free radical production, that is responsible for the lines, wrinkle, and loss of elasticity that we see on our skins. Next, to increase collagen production, we have included Dipalmitoyl Hydroxy Proline and the ASC III Liposome. It has been shown to increase collagen III activity and to decrease collagenase activity. In addition, we have a standardized botanical extract blend that has shown a 24% increase in superficial skin firmness, a 33% increase in deeper skin firmness, a 50% reduction in facial lines, and an 18% increase in skin thickness.
Organic Germanium appears to play a role as an oxygen catalyst, antioxidant, electro-stimulant, and an immune enhancer. Because of its importance, it has actually been dubbed Vitamin O, the oxygen nutrient. It is the single most necessary substance for living. We cannot live for more than three minutes without it. Oxygen even fits the definition of a vitamin, which is a substance found in foods (or the environment, like vitamin D) and necessary for life, but not usually manufactured by the body. Now, another nutrient can be added to the vitamin alphabet mix: Vitamin O, the oxygen nutrient, the very spark of life.
The "magic" of Organic Germanium when it penetrates into your skin structure has been conjectured to be an electric current that is helping to discharge and to balance. Electric fields and energies interact in many complex ways. In Organic Germanium, the atom is so structured that it accepts and transmits electrons, giving it a semiconductor capability. This means it becomes an electro-stimulator, inducing the flow of electricity. It appears to be highly effective in stimulating electrical impulse on a cellular level and in its role as an "Oxygen Catalyst" stimulates the immune system, attacks free radicals, is an antioxidant, and is found in plants such as garlic, aloe, comfrey, ginseng, watercress, and many herbs.
"The holy water of Lourdes, known for its therapeutic value, also contains a quantity of germanium to be worthy of notice, ranging in amounts from 100 to 2,000 parts per million. By 1967, Dr. Asai managed to synthesize a new compound of germanium and found that the manufactured substance itself (bis-beta-carboxyethyl germanium sesquioxide) has amazing curative powers. The product has come to be known as ORGANIC GERMANIUM. (You may wonder how something that is produced synthetically can bear the title "organic." Anything that contains carbon in its molecular architecture is organic, so synthetically derived germanium is organic, according to definition). Early experiments have shown that when germanium is used as a stabilizing agent for tofu, the life of the tofu is extended - it simply does not spoil rapidly."
Dermaxyl (Palmitoyl Oligopeptide-3 or Ceramide-2), is a naturally derived protein that is a fragment of collagen combined with palmitic acid. Research shows that it increases collagen production, hyaluronic acid production, and skin thickness. It reduces surface roughness and depth of wrinkles. This peptide helps to protect the skin's collagen from the effects of UVA and contributes to thickening of the epidermis by promoting collagen renewal, especially when paired with Chlorella Vulgaris extract. This ingredient also has stimulatory activity comparable to that of retinoic acid, but without its drawbacks of irritation.
Palmitoyl Oligopeptide rehydrates the skin by improving the ceramide activity in the skin, assisting in the prevention of DNA damage and the reduction of sun damaged cells. It improves the production of collagen and elastin which helps plump up the skin thus reducing the depth of wrinkles and fine lines and giving the skin a smoother appearance. Dermaxyl is a combination of six natural amino acids which are found in the body and therefore not likely to cause any allergic reactions. It reduces main wrinkle volume by 36%, helps attract cells to sites that need repair and contributes to the reconstruction of the dermis. Ceramide 2 strengthens and repairs the skin's barrier. It improves cell cohesion, enhancing water retention thus reducing skin dryness.
ASC III LIPOSOME (COLLAGEN AMPLIFIER) fights the major cause of wrinkles, the reduction and alteration of the natural collagen support layer that lies beneath the skin. Although collagen-3 is found in abundance in juvenile skin, collagen-1 represents the majority of collagen in adult skin. PS Serums utilize a patented collagen amplifier, ASC III. This industry breakthrough has been clinically tested and shown to stimulate skin cells to produce collagen-3. The patented liposome mechanism allows the ingredient to be absorbed instantly, delivering the nutrients to selectively increase collagen-3 synthesis. The results will promote a plumping and smoothing effect in facial lines and wrinkles.
Active Manuka Honey 20+ has long been documented and used as a skin healer. Our special honey is not only used by doctores on burn patients, it is healing, soothing, contains a variety of natural chemicals and enzymes, some of them synthesized by the plant, others synthesized by the bee. Honey has been found to have anti-bacterial, anti-inflammatory, and anti-fungal activity. These enzymes have natural emollient, humectant, anti-bacterial, and protein digesting properties.
Caigua is a Rainforest Botanical, a cucumber like plant from Peru and is known as a cholesterol herb and seems to be a promising natural therapy for persons with high cholesterol. In turn, this helps skins that are prone to milia.
Cosmeceuticals represent a marriage between "cosmetics and pharmaceuticals". Like cosmetics, cosmeceuticals are topically applied, but they contain ingredients that influence the biological function of the skin. Cosmeceuticals improve appearance, but they do so by delivering nutrients necessary for healthy skin.
Cosmeceutical benefits include facilitating collagen and elastin synthesis, restoring the overall health and functions of photo aged skin as well as facilitate tissue repair. This is why we have included cosmeceuticals into our all natural formulas.
Exposure to ultraviolet light, chemicals and other factors which induce the formation of free radicals causes the skin to age rapidly. Apparent deteriorative oxidative changes triggered by free radicals include wrinkling, hyper pigmentation (excessive tanning) and inflammation (sun burn). A cosmeceutical is an ingredient with medicinal properties which manifests beneficial topical actions or provides protection against degenerative skin conditions.
An analogy of heat and resulting wrinkling of the skin: After repeated dryings in the clothes dryer, a sweater starts out with stretchy material and eventually loses that stretch to where the appearance is one of sagging and lost shape. The same happens with skin due to heat and UV rays from too much sun exposure.
APPLICATIONS OF COSMECEUTICALS
Antimicrobial action Skin conditions such as acne are often of microbial origin, resulting in inflammation and discoloration. Herbal extracts such as curcuminoids, rosemary antioxidants, green tea catechins, alantolactones etc. have the ability to inhibit the growth of microorganisms such as bacteria, fungi and certain viruses.
Anti-irritant/Anti-inflammatory action Irritation and inflammation of the skin are essentially reactions induced by chemicals, environmental pollutants, sunlight and other factors. Anti-inflammatory agents such as curcuminoids inhibit the action of pro-inflammatory enzymes thereby preventing inflammation. Additionally, curcuminoids and ursolic acid also inhibit the enzyme human leukocyte elastase which catalyzes rupture of the cell membranes in inflamed tissues. These compounds therefore help to inhibit inflammation and maintain structural integrity.
Free-radical scavenger action (Anti-oxidant) Free radical chain reactions are implicated in most degenerative biological reactions. Free radicals on the surface of the skin therefore catalyze aging. Antioxidants such as curcuminoids and green tea catechins scavenge free radicals, thereby preventing their formation. Additionally, curcuminoids also inhibit the propagation of free radicals. These antioxidants are therefore useful in anti-aging formulations and in formulations designed to maintain general skin health and integrity. Additionally, these antioxidants also help to maintain the integrity of fat-based topical formulations.
Skin-bleaching action Darker skin tones, patches and blemishes result from increased formation of melanin and slow breakdown of pre-formed melanin on the surface of the skin. Some herbal extracts and phytonutrients regulate the overproduction of melanin through inhibition of the natural enzyme in the skin, tyrosinase, which is responsible for melanin production. Some antioxidant compounds also help to break down pre-formed melanin.
Maintenance of skin texture Aging of the skin is a cumulative effect influenced by factors such as environmental pollution, chemicals, and atmospheric temperature fluctuations The major contributor to skin damage is exposure to sunlight. Ultraviolet A and B radiation from sunlight penetrate the skin and accelerate damage due to free radicals. With prolonged exposure to sunlight, the collagen and elastin fibers which maintain the elasticity and integrity of the skin are broken down by the enzymes collagenase and elastase and the skin texture deteriorates. Herbal extracts and nutrients such as ursolic acid and rosemary extract which inhibit these enzymes and promote collagen and elastin synthesis therefore help to maintain the integrity of the skin Such products are therefore useful in preventing wrinkling and aging and in improving the appearance of photo aged skin. Other compounds that help in improving appearance and texture include alpha-hydroxy acids and aleuritic acid. These compounds accelerate exfoliation thereby helping to soften hardened skin areas.
GENERAL MECHANISMS OF COSMECEUTICAL ACTION
* Prevent the breakdown of collagen and elastin, proteins that maintain the structural integrity of tissues * Enhance healthy cells proliferation * Facilitate tissue repair
One of the most important secrets to a beautiful complexion is deep cell nutrition. Anti-oxidants are imperative for fighting free radical damage, sustaining a beautiful and younger skin. Exceptionally potent amounts of rare and pure pharmaceutical grade ingredients, each designed to effectively target a specific skin problem for a hydrating firming amino peptide nutrients serum that leaves your skin feeling like velvet. Nutrients include Lipopeptide, Cysteine, Lysine, Pentapeptide, Proline, Tyrosine, and amino peptides which make up the building blocks necessary for muscles, ligaments, tendons, organs, glands, hair, nails, body fluids, and wound healing. 90% proanthocyandins (OPCs), a very potent class of anti-oxidant compounds with the presence of taspines. These unique nutrients stimulate the migration of fibroblast cells responsible for tissue regeneration. Naturally occurring vitamin C thirty times more than an orange and ten times as much iron, three times as much niacin, twice as much riboflavin, and fifty percent more phosphorus. It is a significant source of potassium, minerals and amino acids, and supports your skin's firmness and elasticity. Peptides improve skin's resilience, tone and texture while increasing collagen and elastin production for a more youthful appearance.
Great for uneven skin tone. The proprietary blend of skin lightening ingredients ~ Kojic Acid, Lactic Acid, Alpha Arbutin and Botanicals was created to effectively help fade age spots, hyperpigmentation, old acne scars, and uneven skin tone inducing clarity and brightness. Our proprietary blend of skin lightener ingredients is all natural, a super effective lightening blend using multiple lightening agents to attack pigmentation at three levels. First we use lactic acid to exfoliate the highly pigmented outside layer of skin. This allows for better delivery of the other actives to the deeper layers of skin. Next, to prevent melanin synthesis in the lower layers, we use a synergistic blend of tyrosinase inhibitors: kojic acid, mulberry root extract, bearbery extract, and licorice extract. Licorice acts as the 3rd level of attack by counteracting the main trigger of melanin synthesis, which is irritation caused by exposure to UV light. By using multiple skin lightening agents, we can use them at lower levels so they are less irritating as opposed to using higher concentrations of a single active. With consistent use, skin will brighten and age spots fade.
Hyaluronic Acid is virtually unmatched in hydrating the skin, resulting in increased smoothness, softening, elasticity and decreased facial wrinkles.
Natural Moisturizing Factor (NMF) is one of the most important components in your skin. This crucial organic compound regulates how much moisture is being retained by your skin. Nothing can improve the appearance and health of your skin faster than proper skin hydration. The natural moisturizing factor consists of amino acids along with other organic compounds. Amino acids are the basis for all living tissue on Earth. The skin is a living, breathing organ and needs an abundant supply of amino acids to function properly. These natural miracles are the very building blocks needed for the creation of important skin proteins like collagen and elastin.
The selected 17 amino acids in this serum are essential to healthy skin. Without amino acids the skin simply cannot function properly and are the main moisture retention factors in human skin. Topical application of amino acids has shown to dramatically increase moisture content while decreasing visible lines. In addition, amino acids help in the production of collagen and elastin, regulate sebaceous gland activity and decrease discoloration. These are exactly the same amino acids found in collagen and elastin. Each amino acid is made from plant sources and is painstakingly purified. These amino acids are then carefully blended to match the optimum amino acid composition in collagen. By utilizing the unique liposome delivery system, the skin now has available the amino acids necessary to beautify and repair itself on a daily basis.
* Dramatically diminish the appearance of fine lines, wrinkles and age spots (with continued use), by removing dead skin cells to reveal new radiant skin beneath
* Purify and refine pores by drawing out and dissolving deeply embedded dirt and debris
* Resurface skin to improve the texture, tone and elasticity while stimulating the growth of new collagen
DMAE is an amazing nutrient that extends the life of cells, inhibits the cross linking of proteins, which gives the skin a tone and firm appearance. This serum is very light and can be put on over or under the makeup. The firm appearance that DMAE can bring to the skin occurs within about 20 minutes and wears off by the end of the day. DMAE has become very popular as a result of Dr. Nicholas Perricone, M.D.'s top-selling book, The Wrinkle Cure, in which he promotes supplementing with DMAE as a treatment for reducing wrinkles. When applied to the skin DMAE would stimulate acetylcholine release which would trigger a response in the muscles of the face. This activity creates a firmer facial tone and less sagging.
MSM Methylsulfonylmethane is a naturally occurring nutrient found in plants, meats, dairy products, fruits, and vegetables. MSM is therefore found in the normal human diet. It is an odorless, tasteless, white water soluble, crystalline solid in its purified form. MSM supplies sulfur to the body which allows it to heal itself. It produces muscle relaxation and reportedly a whole host of beneficial qualities. It has been used with great success in eliminating chronic pain, muscle pain, repairing cut, scraped, burned and damage skin. We've seen reports of MSM eliminating wrinkles, brown spots, skin tumors, and spider veins. MSM is being used for burn victims and repairing scar tissue. Many people report relief from allergies after using MSM. Other reports indicate that MSM will remove parasites from the body, and help the body to detoxify itself.
MSM is anti-inflamatory and anti-microbial. MSM feeds the formation of collagen and elastin while preventing and reducing cross-linking between cells, which is the primary cause of wrinkles and scar tissue. MSM is a natural sulfur compound that contributes to healthy skin, hair and nails. MSM has been used orally and topically to aid skin disorders. When used topically, in the form of a cream or lotion, sulfur is helpful in treating skin disorders including acne, psoriasis, eczema, dermatitis, dandruff, scabies, diaper rash and certain fungal infections.
Matrixyl 3000 stimulates collagen production in the skin. Hyaluronic Acid is virtually unmatched in hydrating the skin, resulting in increased smoothness, softening, elasticity and decreased facial wrinkles. Matrixyl is one of the newer and more outstanding firming skin ingredients, clinically proven to stimulate collagen by over 300%.